Oral presentation by
Tilahun Ferede Asena on "Modeling Evolution of HIV/AIDS Disease
Progression: A Parametric Semi-Markov Model with Interval Censuring"
Abstract
The introduction of
highly active anti-retroviral therapy (HAART) for the treatment of AIDS
patients has made significant improvements in patient survival and quality of
life during late 1990 (WHO, 2008). Thus, this work focused on estimation of
HIV/AIDS Disease progression using parametric Semi-Markov Models and to assess
factors affecting HIV/AIDS Disease progression of individuals who are following
ART therapy during 2008-2015 with time-dependent covariates in Yirgalim General
Hospital, Ethiopia. The findings of this study indicate that HIV/AIDS Disease
progression can vary greatly according to patient’s gender, Body Mass Index,
and Weight Gain/Loss during the follow-up, Age of the patient and other unknown
factors associated. By including time-dependent covariates, we show that these
factors had significant differences in HIV/AIDS Disease progression. Finally,
these results underscore the need for selecting appropriate waiting time
distribution for each transition in order to accurately estimate disease progression.
In our study, we found that Parametric Semi-Markov models are a powerful
approach for studying chronic diseases and using appropriate waiting times for
specific transitions of disease progression.
Poster Presentation by Hoda
namdari moghadam on the title: Disseminated rectal tuberculosis in an
HIV-seropositive patient: Case report
Abstract
The risk of developing tuberculosis (TB) is estimated to be
between 16-27 times greater in people living with HIV than among those without
HIV infection. The gastrointestinal (GI) tract has been increasingly affected
by tuberculosis, especially in immunocompromised patients. Although strict
rectal involvement is rare, the GI site mostly affected is the ileocecal
region. Thus, tuberculosis should always be considered in the differential
diagnosis of peranal and rectal lesions, and more so in patients infected by
the HIV virus. Author present the case of a man presenting a long-term history
of fever, night sweats, weight loss, bloody diarrhea, fecal incontinence,
tenesmus, and rectal pain. HIV serology was positive. The patient stool sample
stained by ziehle-nelson method, which disclosed the diagnosis of rectal
tuberculosis.
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